Table 1.

Effect of nanoemulsion treatment on biochemical parameters of rats’ serum during the acute dermal toxicity study

	Control		Nanoemulsion
	Male (n = 3) Mean ± SEM	Female (n = 3) Mean ± SEM	Male (n = 3) Mean ± SEM	Female (n = 3) Mean ± SEM
WBC	11.13 ± 0.23	9.07 ± 0.35	11.27 ± 0.32	8.83 ± 0.27
RBC	7.72 ± 0.95	7.27 ± 0.15	7.73 ± 0.18	7.43 ± 0.2
HGB	14.37 ± 0.12	13.23 ± 0.15	14.37 ± 0.2	13.37 ± 0.2
HCT	46.2 ± 1.33	42.73 ± 1.27	45.73 ± 1.78	42.9 ± 1.5
MCV	54.37 ± 1.21	52.33 ± 0.85	54.73 ± 1.16	52.17 ± 1.13
MCH	17.03 ± 0.88	17.7 ± 0.35	17.2 ± 0.21	18.1 ± 0.25
MCHC	33 ± 0.23	33.27 ± 0.55	32.77 ± 0.65	34.43 ± 0.87
PLT	1085.33 ± 20.54	1063.67 ± 20.04	1099.33 ± 8.57	1082.33 ± 17.23
LYM	67.33 ± 2.96	64 ± 0.58	66.33 ± 1.2	62.67 ± 1.2
NEUT	28 ± 2.89	31 ± 1.53	29.67 ± 0.67	32.33 ± 1.2
MONO	3 ± 0.58	3 ± 0.58	2.33 ± 0.33	3 ± 0.58
EOS	1.67 ± 0.33	2 ± 0.58	1.67 ± 0.33	2 ± 0.58

There was no significant difference in hematological parameters between nanoemulsion treated group and control group in male and female rats

WBC (× 1000/mm³) White blood cells, RBC (× 1000/mm³) Red blood cells, HGB (g/dl) Hemoglobin, HCT (%) Hematocrits, MCV (fl) Mean corpuscular volume, MCH (pg) Mean corpuscular hemoglobin, MCHC (g/dl) Mean corpuscular hemoglobin concentration, PLT (× 1000/mm³) Platelets, LYM (%) Lymphocytes, NEUT (%) Neutrophils, MONO (%) Monocytes, EOS (%) Eosinophils