Table 2.
Univariate and multivariate analysis of predictors of failure of the LNG-IUS
| Characteristics | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
| RR | 95% CI | p-value | RR | 95% CI | p-value | |
| Study arm (cohort vs RCT) | 1.02 | 0.76–1.39 | .88 | 1.03 | 0.76–1.38 | .87 |
| Age (≤ 45 vs > 45) | 1.57 | 1.13–2.16 | .004 | 1.51 | 1.10–2.09 | .012 |
| BMI (≥ 25 vs < 25) | 0.91 | 0.67–1.23 | .54 | 0.97 | 0.72–1.31 | .86 |
| Caesarean section | 1.36 | 0.97–1.89 | .10 | |||
| Vaginal delivery | 0.89 | 0.62–1.27 | .49 | |||
| Previous treatment HMB | 1.07 | 0.80–1.45 | .64 | |||
| Anticoagulants | 1.32 | 0.78–2.24 | .52 | |||
| Dysmenorrhea | ||||||
| Present versus non-present | 1.04 | 0.75–1.44 | 0.83 | |||
| Severe versus none/mild/moderate | 1.44 | 1.06–1.94 | .034 | 1.36 | 1.01–1.82 | .041 |
| PBAC-score (≥ 425 vs < 425) | 1.11 | 0.82–1.50 | .49 | 1.08 | 0.81–1.43 | .61 |
BMI, Body Mass Index; HMB, heavy menstrual bleeding; PBAC, Pictorial Blood Assessment Chart. Imputed data: BMI n = 60, caesarean section N = 3, previous treatment HMB N = 1, anticoagulants N = 1, dysmenorrhea N = 12, PBAC = 39. Multivariate analysis preceded by a forced entry method