Table 2.

Subgroup analyses of QOL between PD patients and healthy controls

Subgroups		Categories (number of studies)	Sample size		SMD	95% CI		I2	P within subgroup	Q (P value across subgropus)
			PD	HC		Lower	Upper
Domain	Physical	WHOQOL (3)	169	354	−0.866	−1.067	−0.665	0	<0.001	1.351 (P = 0.245)
		SF (7)	724	148,921	−0.866	−1.593	−0.139	98.216	<0.001
	Mental	WHOQOL (3)	169	354	−0.503	−0.699	−0.306	0	0.557	0 (P = 0.989)
		SF (7)	724	148,921	−0.598	−0.907	−0.289	89.961	<0.001
Measurement of QOL	/	EQ‐5D (4)	1412	1098	−0.889	−1.181	−0.596	85.787	<0.001	188.353 (P < 0.001)
		EQ‐VAS (5)	1444	952	−1.081	−1.578	−0.584	94.362	<0.001
		PDQ‐39 (4)	251	198	−1.384	−1.607	−1.162	7.645	0.355
		SF(7)	724	148,921	−0.423	−1.131	0.285	98.194	<0.001