Table 2.
Cardiac manifestations of PIMS-TS.
| Variable | Number of Study | n/N | Mean (SD) | % | |
|---|---|---|---|---|---|
| Sign of shock | 24 | 652/1288 | 50.62 | ||
| respiratory distress/failure | 24 | 270/1288 | 20.96 | ||
| Radiography | Normal | 9 | 25/751 | 3.33 | |
| Cardiomegaly + Pericardial effusion | 164/751 | 21.84 | |||
| Pleural effusion | 105/751 | 13.98 | |||
| focal/bilateral opacity | 169/751 | 22.50 | |||
| lung oedema | 16/751 | 2.13 | |||
| Atelectasis | 10/751 | 1.33 | |||
| interstitial abnormalities | 9/751 | 1.20 | |||
| Reactive airway disease | 2/751 | 0.27 | |||
| Electrocardiography | Junctional rhytm | 7 | 3/212 | 1.42 | |
| Sinus Bradycardia | 1/212 | 0.47 | |||
| Supraventricular extrasystole | 1/212 | 0.47 | |||
| Attenuated QRS | 1/212 | 0.47 | |||
| AV block | 5/212 | 2.36 | |||
| PR Interval abnormalities | 2/212 | 0.94 | |||
| QT abnormalities | 1/212 | 0.47 | |||
| T wave abnormalitis | 21/212 | 9.91 | |||
| Atrial Fibrillation | 1/212 | 0.47 | |||
| Ventricular arrhytmia (VT/VF/PVC) | 4/212 | 1.89 | |||
| ST abnormalities | 34/212 | 16.04 | |||
| Various Troponin Level | Troponin I | 3 | 869 (1229) | ||
| Troponin T | 3 | 75 (132) | |||
| High sensitivity troponin I | 3 | 1183 (3307) | |||
| Unspecified troponin | 7 | 1277 (10114) | |||
| Elevated troponin I | 4 | 50/67 | 74.63 | ||
| Elevated sensitivity troponin I | 3 | 61/68 | 89.7 | ||
| Elevated unspecified | 7 | 335/718 | 46.66 | ||
| BNP (pg/mL) | 4 | 4238.35 (5803.24) | |||
| NT-proBNP (pg/mL) | 10 | 13,590.78 (20,676.1) | |||
| Echocardiography | Mitral Regurgitation | 22 | 175/1174 | 14.91 | |
| Tricuspid Regurgitation | 19/1174 | 1.62 | |||
| Pericardial Effusion + pericarditis | 221/1267 | 17.44 | |||
| Myocarditis | 196/1267 | 15.47 | |||
| RV dysfunction | 17/1174 | 1.45 | |||
| Biventricular systolic dysfunction | 1/1174 | 0.09 | |||
| Coronary Echogenicity | 17/1174 | 1.45 | |||
| Coronary artery dilatation | 42/1174 | 3.58 | |||
| Coronary artery aneurysm | 45/1267 | 3.55 | |||
| Unspecified valvular regurgitation | 2/1174 | 0.17 | |||
| Coronary artery dilatation or aneurysm | 95/1174 | 8.09 | |||
| Biventricular or left ventricular dysfunction | 5/1174 | 0.43 | |||
| Ectatic coronary artery | 14/1174 | 1.19 | |||
| Myocardial dysfunction | 15/1174 | 1.28 | |||
| Unspecified coronary abnormalities | 4/1174 | 0.34 | |||
| Echocardiography | Cardiomegaly | 2/1174 | 0.17 | ||
| Regional wall motion abnormal | 3/1174 | 0.26 | |||
| Lack of distal tapering LAD coronary artery | 11/1174 | 0.94 | |||
| Dilated left ventricle | 1/1174 | 0.09 | |||
| Diastolic dysfunction | 2/1174 | 0.17 | |||
| Left ventricle dysfunction | 107/1174 | 8.45 | |||
| LVEF | > 55% | 13 | 33/305 | 10.82 | |
| < 55% | 180/305 | 59.02 | |||
| N/A | 80/305 | 26.23 | |||
| Coronary Artery Z score |
< 2 | 13 | 11/139 | 7.91 | |
| 2–2.5 | 9/139 | 6.47 | |||
| ≥ 2.5 | 18/138 | 12.95 | |||
AV; atrioventricular, BNP; brain natriuretic peptide, NT-proBNP; N-terminal-pro brain natriuretic peptide, RV; right ventricular, LVEF; left ventricular ejection fraction, N/A; not available.