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. 2020 Dec 10;143(3):031004. doi: 10.1115/1.4049017

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Impact zones for different proteins. (a) Contour plot of impact zone as a function of Ea and A0. The shaded region suggests that molecular hyperthermia can inactivate proteins effectively. The open dots are experimental measurements of Ea and A0 for different proteins from Table 4. The solid line indicates the empirical correlation between Ea and A0 [68]. (b) Impact zones calculated based on the Ea–A0 correlation (solid line) and real protein kinetic parameters (open dots). The thermally unstable proteins are not plotted on the figure since they have unrealistic impact zones. — Impact zones for different proteins. (a) Contour plot of impact zone as a function of E_a and A₀. The shaded region suggests that molecular hyperthermia can inactivate proteins effectively. The open dots are experimental measurements of E_a and A₀ for different proteins from Table 4. The solid line indicates the empirical correlation between E_a and A₀ [68]. (b) Impact zones calculated based on the E_a–A₀ correlation (solid line) and real protein kinetic parameters (open dots). The thermally unstable proteins are not plotted on the figure since they have unrealistic impact zones.