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. Author manuscript; available in PMC: 2021 Feb 19.
Published in final edited form as: Nature. 2020 Aug 19;586(7830):606–611. doi: 10.1038/s41586-020-2631-z

Extended Data Fig. 11. IFNγ-induced changes in wHILOs.

Extended Data Fig. 11.

a, Venn diagram of differentially regulated genes upon acute (12h at 10 ng/ml) and multi pulse stimulated (MPS; 2h at 10 ng/ml for 3 days) IFNγ treatment of wHILOs. b, Heatmap of differentially expressed genes upon acute and MPS IFNγ stimulation. Sustainable PD-L1 gene expression by MPS is indicated. c, Gene ontology of selectively regulated genes upon MPS-IFNγ (top panel) and acute IFNγ (bottom panel) treatments. d, Browser tracks showing chromatin accessibility at selected genes 7 days after last IFNγ treatment in MPS or 12 hours after acute IFNγ stimulation in wHILOs. Data were from triplicate (a-c) or duplicate (d) samples.