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. Author manuscript; available in PMC: 2021 Feb 19.
Published in final edited form as: Nature. 2020 Aug 19;586(7830):606–611. doi: 10.1038/s41586-020-2631-z

Extended Data Fig. 2. WNT expression in human islets.

Extended Data Fig. 2.

a, Heatmap of relative expression of WNTs in human islets (n=5). b, tSNE clustering of human islet single cell transcriptomes (n= 3245). Annotated cell types assigned based on known marker gene expression. c, Heatmap of expression of top 10 signature genes in human islet cell clusters from Fig. 1b. d, Single cell expression of signature hormonal and cell type-specific genes in human islets. e,f, Single cell (e) and violin plots (f) of WNT2B, WNT4, WNT5A, WNT7A, WNT7B and WNT9A expression in human islets, statistics provided in Supplementary Table 5. Data from 3 pooled human islets (b-f).