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. Author manuscript; available in PMC: 2021 Feb 9.
Published in final edited form as: Microb Pathog. 2018 Dec 5;127:212–219. doi: 10.1016/j.micpath.2018.12.008

Fig. 3. Specific leukocytes were reduced in the airways of CD14 null mice during co-morbidity.

Fig. 3.

While disease states led to a reduction in the number of macrophages in wild-type (WT) and knowckout (KO) mice in general, flow cytometric analyses revealed no differences between WT and KO mice (A). Eosinophils were prominent after allergen exposure but were significantly reduced in the KO mice with asthma and influenza (B), while neutrophils were dominant in both genotypes after virus infection in the absence of asthma (C). Lymphocytes (D, E, and F) followed similar trends wherein KO mice had less infiltration of these cells in co-morbidity. Data are represented as the mean and SD of n = 5 mice per group per genotype and analyzed with two-way ANOVA with Tukey’s multiple comparisons test. Data are significant (p < 0.05) when letters above bars are dissimilar.