Table 1.
Stratum |
1 |
2 |
||
---|---|---|---|---|
Dose: | Dose Level 1 8 Gy x 2 (n = 6) |
Dose Level 2 8 Gy x 3 (n = 4) |
Dose Level 1 6 Gy x 2 (n = 6) |
Dose Level 2 6 Gy x 3 (n = 6) |
Site of index (irradiated) lesion | Lung | lung | liver/ subcutaneous |
liver/ subcutaneous |
Prior Therapy* | ||||
Treatment-naïve | 2 (33%) | 3 (75%) | 3 (50%) | 3 (50%) |
Treatment-refractory | 4 (67%) | 1 (25%) | 3 (50%) | 3 (50%) |
Stage | ||||
M1a | 0 | 0 | 0 | 2 (33%) |
M1b | 2 (33%) | 2 (50%) | 0 | 2 (33%) |
M1c | 4 (67%) | 2 (50%) | 6 (100%) | 2 (33%) |
LDH | ||||
Elevated | 4 (67%) | 1 (25%) | 3 (50%) | 2 (50%) |
Not elevated | 2 (33%) | 3 (75%) | 3 (50%) | 2 (50%) |
Gender | ||||
Male | 5 (83%) | 2 (50) | 5 (83) | 5 (83) |
Female | 1 (17%) | 2 (50) | 1 (17%) | 1 (17%) |
Patient age in years, n (%) | ||||
18–44 | 0 | 0 | 0 | 0 |
45–64 | 3 (50) | 3 (75) | 2 (33) | 0 |
≥65 | 3 (50) | 1 (25%) | 4 (67) | 6 (100) |
Patients with ECOG PS, n (%) | ||||
0 | 4 (67) | 3 (75) | 3 (50) | 2 (33) |
1 | 2 (33) | 1 (25%) | 3 (50) | 4 (67) |
*Prior Therapies Detailed in Supplemental Table 1.