Table 3.
Study subject # | Radiation site | Stratum | Dose | Best distant response (RECIST) | Time to progression from RT (months) | Therapy at progression | Status at last f/u | Time from RT to last f/u or death (months) |
---|---|---|---|---|---|---|---|---|
1 | Lung | 1 | 8 Gy x 2 | SD | 9.8 | SBRT to new lung lesion; resection of brain met; pembro | Alive; SD on pembro | 97.4 |
8 | Lung | 1 | 8 Gy x 2 | PD | 5.4 | pembro | Alive; SD on pembro | 36.7 |
10 | Liver | 2 | 6 Gy x 2 | PR | N/A | N/A | NED | 88.7 |
16 | Lung | 1 | 8 Gy x 3 | PR | 12.2 | Gamma Knife and resection of brain mets; then pembro | Stable disease on pembro | 82.6 |
17 | Axillary nodal mass | 2 | 6 Gy x 3 | PD | 3.3 | pembro; then progressed in breast; mastectomy; placed on B-raf inhibitors | Alive; SD on B-Raf inhibitors | 82.2 |
20 | Lung | 1 | 8 Gy x 3 | SD | 7.6 | pembro | SD on pembro | 24.9 |
22 | Lung | 1 | 8 Gy x 3 | PR | 12.3 | pembro | Stable disease on pembro | 57.6 |