Fig 4.

Therapeutic administration of GSK2593074A (GSK’074) decreases macrophage population within the aortic wall. Immunostaining and quantification of F4/80 (A), CD206 (B), major histocompatibility complex II (MHCII) (C), and IL-1β (D) of aortic cross-sections from dimethylsulfoxide (DMSO) and GSK’074-treated aortas 28 days after AAA induction. n = 6 for each group. Data are presented as mean ± standard error. A two-tailed Student t-test was performed. ∗P ≤ .05. DAPI, 4',6-diamidino-2-phenylindole.