Table 3.
Parameters |
Targeted Therapy (n = 26) |
Cytokine Therapy (n = 74) |
P
Value |
Sex, n | 1.000 | ||
Male | 20 | 56 | |
Female | 6 | 18 | |
Age, mean (95% CI), y | 57.1 (52.5–61.8) | 59.8 (56.7–62.9) | |
No. of levels | .015* | ||
1 | 15 | 57 | |
2 | 11 | 11 | |
3 | 0 | 3 | |
Neurological status before surgery, n | <.0001* | ||
Frankel A, B, C | 3 | 47 | |
Frankel D, E | 23 | 27 | |
Revised Tokuhashi score, mean (95% CI) | 11.1 (10.2–12.0) | 11.6 (11.1–12.1) | .328 |
SINS, mean (95% CI) | 11.3 (9.6–13.1) | 10.9 (9.9–11.9) | .458 |
Metastases, n | |||
Synchronous | 11 | 55 | .007* |
Solitary spinal metastases | 2 | 6 | 1.000 |
Extravertebral bone metastases, n | 13 | 29 | .364 |
Additional visceral metastases | 13 | 37 | 1.000 |
Radical nephrectomy prior spine surgery, n | 24 | 63 | .505 |
Metastasectomy, n | 7 | 32 | .167 |
Abbreviation: CI, confidence interval; SINS, Spinal Instability Neoplastic Score.
Statistically significant difference.