Skip to main content
. 2021 Jan 27;2021:1297378. doi: 10.1155/2021/1297378

Figure 1.

Figure 1

Egr-1 knockout (KO) decreased ICAM-1 expression. (a) Venous ECs from WT and Egr-1 KO mice were isolated and stimulated with mechanical stretch from 0 to 3 h (n = 5). ICAM-1 mRNA expression was determined by real-time RT-PCR. (b) Egr-1 KO decreased ICAM-1 protein levels after mechanical stretch stimulation for 24 h (n = 5). Data are expressed as mean ± SEM. ∗P < 0.05 versus the WT group; #P < 0.05 versus the WT/ST group. (c) Egr-1 KO decreased ICAM-1 mRNA expression in the mouse vein graft model (n = 5). Data are expressed as mean ± SEM. ∗P < 0.05 versus the WT group. WT: wild-type mice; WT/ST: venous ECs from WT mice stimulated with mechanical stretch; Egr-1 KO: Egr-1 knockout mice; Egr-1 KO/ST: venous ECs from Egr-1 knockout mice stimulated with mechanical stretch.