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. 2021 Feb 2;2021:6637584. doi: 10.1155/2021/6637584

Table 2.

Effects of the aqueous and methanol extracts of the N. pobeguinii on body weight during 6 weeks after injection of streptozotocin in mice.

Treatment Dose (mg/kg) Period (week)
0 1 2 3 4 5 6
Normal control 32.00 ± 0.88 34.00 ± 1.57 36.33 ± 0.80 38.00 ± 0.82 38.50 ± 1.50 40.00 ± 0.93 40.77 ± 0.99

Diabetic control 35.67 ± 1.52 33.50 ± 0.81 31.17 ± 0.60α 30.17 ± 0.89λ 29.67 ± 0.92λ 28.17 ± 0.79λ 27.00 ± 0.52λ

Pregabalin 30 33.50 ± 1.92 31.17 ± 1.28 30.50 ± 1.29β 29.50 ± 1.15λ 28.41 ± 1.43λ 27.83 ± 1.20λ 26.09 ± 0.73λ

Aqueous extract 150 34.12 ± 1.69 33.50 ± 0.96 31.17 ± 0.46α 32.00 ± 0.37λ 34.22 ± 0.28 34.50 ± 0.22βc 35.00 ± 0.58λc
300 34.51 ± 2.03 33.67 ± 0.81 31.83 ± 0.52 32.17 ± 0.48λ 34.33 ± 0.25 36.00 ± 0.32c 36.67 ± 0.42βc

Methanol extract 150 35.18 ± 1.37 34.17 ± 1.49 30.67 ± 0.60β 31.67 ± 0.42λ 33.00 ± 0.68α 33.67 ± 0.68λb 34.08 ± 0.58λc
300 32.33 ± 2.17 30.19 ± 1.85 29.40 ± 1.74λ 29.18 ± 1.50λ 30.67 ± 1.43λ 31.33 ± 1.33λ 32.39 ± 1.15λc

All values are expressed as the mean ± SEM of six animals per experimental group, compared by one-way analysis of variance followed by Tukey test; αp <0.05, βp <0.01, λp <0.001 mean significantly different from the normal control group (nondiabetic); and bp <0.01, cp <0.001 mean significantly different from the diabetic control group.