Table 3.
Changes of laboratory data for the 66 survivors
| Baseline | Day 5–8 | p value* | |
|---|---|---|---|
| WBC (109/L) | 6.21 ± 1.97 | 5.87 ± 1.66 | 0.10 |
| Neu (109/L) | 3.99 ± 1.86 | 3.50 ± 1.51 | 0.02 |
| Lym (109/L) | 1.49 ± 0.59 | 1.60 ± 0.47 | 0.04 |
| BUN (mmol/L)a | 4.10 (3.18, 5.25) | 4.00 (3.30, 4.63) | 0.36 |
| Creatinine (µmol/L)a | 65.0 (52.0, 79.3) | 67.0 (54.0, 84.5) | 0.06 |
| d-dimer (µg/mL FEU)a | 0.43 (0.22, 1.15) | 0.27 (0.22, 0.69) | 0.001 |
| NT-proBNP (pg/mL)a | 67.0 (29.3, 163.8) | 51.5 (24.5, 149.5) | 0.01 |
| TnI (pg/mL)a | 2.25 (1.90, 4.90) | 1.90 (1.90, 3.18) | <0.001 |
| CRP (mg/L)a | 3.0 (0.7, 17.4) | 1.3 (0.7, 5.3) | 0.001 |
| Interleukin-6 (pg/mL)a | 2.8 (1.5, 6.9) | 3.2 (1.5, 6.0) | 0.56 |
WBC white blood cell counts, Neu neutrophil counts, Lym lymphocyte counts, BUN blood urea nitrogen, Cr creatinine, NT-proBNP N-terminal pro-B-type natriuretic peptide, TnI troponin I, CRP c-reactive protein
*p values for the comparison of biomarkers at baseline and day 5–8. Paired t test or Wilcoxon rank sum test according to the characteristics of distribution
aMedian (interquartile range)