Table 5.
Univariate and multivariate Cox regression analyses revealing predictive value of laboratory data changes for patient death
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Age | 1.10 (1.03, 1.18) | 0.004 | 1.17 (1.04, 1.31) | 0.007 |
| Gender (female) | 0.42 (0.10, 1.67) | 0.22 | ||
| Comorbidities | 2.45 (0.61, 9.81) | 0.21 | ||
| RWBC | 12.63 (4.06, 39.24) | < 0.001 | 63.80 (5.60, 727.34) | 0.001 |
| RNeu | 1.44 (1.10, 1.87) | 0.007 | ||
| RLym | 0.003 (0.000, 0.046) | < 0.001 | ||
| RBUN | 2.45 (1.44, 4.17) | 0.001 | ||
| RCr | 1.61 (0.29, 8.88) | 0.58 | ||
| Rd-dimer | 1.15 (1.06, 1.26) | 0.002 | ||
| RNT-proBNP | 1.18 (1.06, 1.31) | 0.002 | ||
| RTnI | 1.17 (1.07, 1.27) | < 0.001 | 1.34 (1.12, 1.62) | 0.002 |
| RCRP | 0.96 (0.57, 1. 59) | 0.86 | ||
| RIL-6 | 1.24 (1.04, 1.48) | 0.02 | 1.32 (1.05, 1.66) | 0.02 |
WBC white blood cell counts, Neu neutrophil counts, Lym lymphocyte counts, BUN blood urea nitrogen, Cr creatinine, NT-proBNP N-terminal pro-B-type natriuretic peptide, TnI troponin I, CRP c-reactive protein, IL-6 Interleukin-6
R = laboratory data at day 5–8/laboratory data at admission