Table 3.
Likelihood of recovery, hospitalization, or death during the first 14 days after the onset of COVID-19 symptoms among cases treated with TNR4 versus those in the comparison group.
| Type of treatment | Recovery within 14 days after onset of symptoms | Hospitalization within 14 days after onset of symptoms | Death within 14 days after onset of symptoms |
|---|---|---|---|
| Yes (n = 575) | Yes (n = 133) | Yes (n = 67) | |
| Odds Ratio (95% CI; p-value) | Odds Ratio (95% CI; p-value) | Odds Ratio (95% CI; p-value) | |
| aComparison group, all participants (n = 287) | Reference | Reference | Reference |
| TNR4, all participants (n = 481) | 3.4 (2.38–4.96; p = 0.000) | 0.25 (0.16–0.38; p = 0.000) | 0.19 (0.10–0.36; p = 0.000) |
| aComparison group with comorbidities (n = 131) | Reference | Reference | Reference |
| TNR4 with comorbidities (n = 185) | 3.5 (2.12–5.78; p = 0.000) | 0.24 (0.14–0.41; p = 0.000) | 0.22 (0.10–0.47; p = 0.000) |
| aComparison group, cases between 18–35 years (n = 77) | Reference | Reference | Reference |
| TNR4, cases between 18–35 years (n = 181) | 3.0(1.38–6.39; p = 0.005) | 0.23 (0.09–0.60; p = 0.003) | – |
| aComparison group, cases between 36–48 years (n = 91) | Reference | Reference | Reference |
| TNR4, cases between 36–48 years (n = 163) | 3.6 (1.94–6.58; p = 0.000) | 0.15 (0.06–0.33; p = 0.000) | 0.06 (0.01–0.48; p = 0.008) |
| aComparison group, cases between 49–80 years (n = 119) | Reference | Reference | Reference |
| aTNR4, cases between 49–80 years (n = 137) | 4.0 (2.25–7.08; p = 0.000) | 0.32 (0.18–0.58; p = 0.000) | 0.22 (0.11–0.45; p = 0.000) |
| aComparison group, males (n = 161) | Reference | Reference | Reference |
| TNR4, males (n = 226) | 3.9 (2.27–6.62; p = 0.000) | 0.24 (0.12–0.45; p = 0.000) | 0.18 (0.08–0.43; p = 0.000) |
| aComparison group, health workers (n = 38) | Reference | Reference | Reference |
| TNR4, health workers (n = 104) | 1.9 (0.88–3.99; p = 0.102) | 0.34 (0.09–1.28; p = 0.111) | 0.26 (0.02–3.55; p = 0.311) |
95% Confidence Intervals (CIS) were estimated with multivariate logistic regression models adjusted by age, sex, comorbidities, and occupation.
a
Comparison group: participants who did not accept the TNR4 treatment because they were asymptomatic, were already taking another treatment, or they had self-medicated for cold and flu. However, they agreed to take part in the follow-up portion of the study.