Table 5. Comparison of grade 3 well-differentiated neuroendocrine tumors and poorly differentiated neuroendocrine carcinomas with respect to clinicopathological characteristics.

*Fisher’s exact test was applied.

**Mean ± SD (standard deviation), independent t-test was applied.

WDNET, Well-differentiated neuroendocrine tumor; PDNEC, poorly differentiated neuroendocrine carcinoma.

Clinicopathological characteristics	Frequency (%)		p value
	Grade 3 WDNET (n = 14)	PDNEC (n = 6)
			Gender*
Male	10 (71.4)	2 (33.3)	0.161
Female	4 (28.6)	4 (66.7)
Age (years)**	53.3 ± 19.3	61.7 ± 14.4	0.354
Age groups*
<30 years	2 (14.3)	0 (0)	1
31–50 years	4 (28.6)	2 (33.3)
>50 years	8 (57.1)	4 (66.7)
Ki67 (%)**	60.7 ± 21.4	76.7 ± 10.3	0.102
Tumor site*
Gastrointestinal tract	10 (71.4)	4 (66.7)	1
Pancreatobiliary tract	4 (28.6)	2 (33.3)
Individual tumor sites*
Rectum	2 (14.3)	2 (33.3)	0.757
Stomach	2 (14.3)	0 (0)
Small bowel	6 (42.9)	2 (33.3)
Pancreas	4 (28.6)	2 (33.3)