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. 2021 Feb 5;14:267–285. doi: 10.2147/JIR.S278395

Table 3.

Key Regulated Factors of CC Chemokine Receptors in LUAD (TRRUST)

Key TF Description Regulated Gene P value FDR
NR3C2 nuclear receptor subfamily 3, group C, member 2 CCR5, CCR6 6.48E-06 1.97E-05
KLF2 Kruppel-like factor 2 (lung) CCR5, CCR7 1.69E-05 1.97E-05
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) CCR2, CCR3, CCR5,CCR7 1.92E-05 1.97E-05
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 CCR2,CCR3,
CCR5,CCR7
1.97E-05 1.97E-05

Abbreviations: LUAD, lung adenocarcinoma; TF, transcription factor; FDR, false discovery rate.