Table 3.
Key Regulated Factors of CC Chemokine Receptors in LUAD (TRRUST)
Key TF | Description | Regulated Gene | P value | FDR |
---|---|---|---|---|
NR3C2 | nuclear receptor subfamily 3, group C, member 2 | CCR5, CCR6 | 6.48E-06 | 1.97E-05 |
KLF2 | Kruppel-like factor 2 (lung) | CCR5, CCR7 | 1.69E-05 | 1.97E-05 |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | CCR2, CCR3, CCR5,CCR7 | 1.92E-05 | 1.97E-05 |
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
CCR2,CCR3, CCR5,CCR7 |
1.97E-05 | 1.97E-05 |
Abbreviations: LUAD, lung adenocarcinoma; TF, transcription factor; FDR, false discovery rate.