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. 2021 Feb 5;13:1099–1111. doi: 10.2147/CMAR.S278023

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© 2021 Si et al.

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Celastrol performed a potential anti-tumor effect on HCC in vitro. Huh7 and Hep3B cells were treated with mock, 0.5 or 1 µM of celastrol (Cela) for 48 h. (A) Colony formation assay for the colony formation capacity of treated cells. (B and C) MTS assay for cell proliferation. (D and E) Transwell assay for cell migration and invasion. (F) Flow cytometry for cell apoptosis. n = 3; data were presented as mean ± SD; *P < 0.05, **P < 0.01, ***P < 0.001 or ****P < 0.0001 vs Control.