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. 2021 Jan 27;11:606689. doi: 10.3389/fphar.2020.606689

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Copyright © 2021 Li, Cao, Lu, Li, Pang, Fu, Fang, Chen, Liu, Wu, Zhou and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of ZWT on kidney function and colonic injury. (A) Effect of ZWT on body weight, kidney index, spleen index, and biochemical parameters including urine volume, 24-h urine protein, BUN, and CRE. (B) Photomicrographs of HE staining (400×), PAS staining (400×), and immunofluorescence staining (200×) of IgA and C3 immune complexes in glomeruli of renal tissues and HE staining (200×) of colon tissues in IgAN rats. Values represent mean ± SD, n = 5. Vertical bars represent standard deviation of the mean. ^# p < 0.05, ^## p < 0.01 vs. normal; *p < 0.05, **p < 0.01 vs. model.