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. 2021 Jan 27;12:615451. doi: 10.3389/fnagi.2020.615451

Table 1.

Registered drugs targeting mitochondrial dysfunction on ClinicalTrials.gov.

Condition/Disease Status Phase Treatment Trial number
Parkinson's disease Completed 2 Mitoquinone NCT00329056
Stroke Completed 2 Cyclosporin A NCT01527240
Glucose metabolism disorders Active, not recruiting Not applicable NMN NCT03151239
Progressive supranuclear palsy Neurological disorders Completed 2 and 3 CoQ10 NCT00532571
Sleep disorder Traumatic brain injury Withdrawn 2 Tesamorelin NCT02931474
Mild cognitive impairment Recruiting 1 Niagen® NCT03482167
Friedreich's ataxia Completed 3 Idebenone NCT01303406
Brain tumor treated with cranial or cranial-spinal radiation Completed 3 Metformin NCT02040376
Cerebral infarction Completed 4 Edaravone NCT00200356