Table 2.

Characteristics of ROC curve for significantly dysregulated proteins.

	p value	AUC (%)	SEN (%)	SPE (%)	PPV (%)	NPV (%)
AHSG
All cases	0.002**	66.80	60	69.39	62	69
T1	0.24	55.2	–	–	–	–
T2	< 0.0001***	72.9	68.8	85.7	75.9	80.8
N0	0.001**	69.3	62.5	87.8	71.4	82.7
N+	0.001**	63.9	50.0	85.7	65.0	76.4
KRT6C
All cases	0.008**	64	60	63.26	64	63
T1	0.180	52.4	–	–	–	–
T2	< 0.0001***	75.8	68.8	79.6	68.8	79.6
N0	0.005**	69.5	50.0	85.7	63.2	77.8
N+	0.0009***	65.5	50.0	89.8	72.2	77.2
KLK1
All cases	0.005**	66	58	69.39	58	69
T1	0.03*	67.0	55.6	83.7	55.6	83.7
T2	0.02*	64.9	31.3	98.0	100.0	69.0
N0	0.007**	69.3	45.8	91.8	73.3	77.6
N+	0.08	62.3	–	–	–	-
BPIFB2
All cases	0.003**	66	70	64.58	72	65
T1	0.003**	80.5	88.9	69.4	51.6	94.4
T2	0.32	58.2	–	–	–	–
N0	0.004**	70.7	79.2	63.3	51.4	86.1
N+	0.08	62.1	–	–	–	–
AZGP1
All cases	< 0.0001***	72.80	74	74.83	74	71
T1	0.004**	71.8	83.3	53.1	39.5	89.7
T2	0.004**	72.2	75.0	69.4	61.5	81
N0	< 0.0001***	76.5	75.0	69.4	54.5	85
N+	0.05*	67.9	69.2	69.4	54.5	81

AUC area under the curve, SEN sensitivity, SPE specificity, PPV: predictive value, NPV negative predictive value.

Bold values indicate statistical significance (p < 0.05).