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. 2020 Oct 26;476(2):699–713. doi: 10.1007/s11010-020-03937-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — MSC-AS1 was highly expressed in TMZ-resistant in glioma cells and tissues. a 40 Up-regulated lncRNAs in TMZ-resistant glioma cell line (229R) compared to its parental cell line (LN299) were shown from downloaded the GSE113510 dataset. b MSC-AS1 expression in glioma and normal tissues, TMZ-resistant, and TMZ-sensitive glioma tissues was measured by qRT-PCR. c MSC-AS1 expression in LN229/TR and SHG-44/TR cells compared to their parental cells (LN229 and SHG-44) was analyzed by qRT-PCR. d The overall survival rate in glioma patients with high MSC-AS1 expression compared to patients with low MSC-AS1 expression was evaluated using Kaplan–Meier overall survival curve. e The diagnostic efficiency of MSC-AS1 in glioma. f The levels of MCL-1 and MRP-1 in TMZ-resistant and TMZ-sensitive glioma tissues were measured by western blot. *P < 0.05