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. 2021 Feb 9;11:3426. doi: 10.1038/s41598-021-83022-5

Figure 5.

Figure 5

CXCR7 expression in cardiomyocytes is increased in heart failure patients. (a) Violin plots of CXCR7 mRNA expression based on single-cardiomyocyte RNA-seq of human heart specimens obtained from control subjects (n = 156) and patients with heart failure (n = 678). Significance was calculated by the Mann–Whitney test; ***P < 0.001 (b) Violin plots of CXCR7 mRNA expression based on bulk RNA-seq of human failing hearts before and after LVAD implantation. Analysis was performed using publicly available data20. Significance was calculated by ANOVA followed by the Bonferroni procedure; ***P < 0.001. ICM, ischemic cardiomyopathy; NICM, non-ischemic cardiomyopathy.