Table 3.
Resting state pairwise connections in individuals with food addiction compared to individuals with no food addiction.
| Food addiction versus no food addiction | ||||||||
|---|---|---|---|---|---|---|---|---|
| Network | Analysis unit | Network | Analysis unit | df | t | p-value | q-value | Interpretation |
| Brainstem 113 connections | ||||||||
| Bst | L MRF | CEN | L_MFG (R_ContB_PFClv_3) | 146 | 4.05 | 8.28E−05 | 0.02 | Greater |
| Bst | L_MRF | CAN | R_OrG, (R_ContB_PFClv_2) | 146 | 3.98 | 1.08E−04 | 0.02 | Greater |
| Bst | L_MRF | CAN | L_OrG, (L_ContB_PFClv_1) | 146 | 3.89 | 1.52E−04 | 0.02 | Greater |
| Emotional regulation (ERN) network connections | ||||||||
| ERN | L_InfFS, (R_ContA_PFCl_2) | SMN | R_PosCG, (R_SomMotA_16) | 146 | − 4.00 | 1.00E−04 | 0.04 | Lower |
| Sensorimotor (SMN) network connections | ||||||||
| SMN | R_PosCG, (R_SomMotA_16) | DMN | R_MTG, (R_TempPar_6) | 146 | − 4.11 | 6.57E−05 | 0.03 | Lower |
Summarizes significant disease-related differences in functional connectivity (individuals with food addiction vs. individuals with no food addiction). All connections are significant q < 0.05.
Bst, Brainstem; CAN, Central Autonomic Network; CEN, Central Executive Network; DMN, Default Mode Network; ERN, Emotional Regulation Network; InfFS, Inferior frontal sulcus; MFG, Middle frontal gyrus; MRF, Mesencephalic reticular formation; MTG, Middle Temporal Gyrus; OrG, Orbital gyri; PosCG, Postcentral Gyrus; SMN, Sensorimotor Network.
df: degrees of freedom; p value significant < .05, q value (corrected for multiple comparisons) < .05.