Table 4.
Resting state pairwise connections in females with food addiction compared to males with food addiction.
| Females with food addiction versus males with food addiction | ||||||||
|---|---|---|---|---|---|---|---|---|
| Network | Analysis unit | Network | Analysis unit | df | t | p-value | q-value | Interpretation |
| Emotional regulation (ERN) network connections | ||||||||
| ERN | L_InfFGTrip (L_DefaultB_PFCv_4) | SMN | L_PaCL_S (L_SomMotA_6) | 147 | 3.99 | 1.04E-04 | 0.04 | Greater |
| Salience (SAL) network connections | ||||||||
| SAL | L_ShoInG (L_SalVentAttnA_Ins_1) | SMN | L_PaCL_S (L_SomMotA_13) | 147 | 4.31 | 2.97E-05 | 0.01 | Greater |
| SAL | R_MPosCgG_S, (R_SalVentAttnA_ParMed_1) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | 3.64 | 3.77E-04 | 0.03 | Greater |
| Sensorimotor (SMN) network connections | ||||||||
| SMN | R_SupFG, (R_DefaultA_PFCm_5) | SMN | L_MOcS_LuS, (L_VisCent_ExStr_8) | 147 | − 3.98 | 1.08E−04 | 0.04 | Lower |
| SMN | L_PaCL_S (L_SomMotA_19) | CEN | L_MFG (L_ContB_PFCd_1) | 147 | 4.54 | 1.16E−05 | 0.01 | Greater |
| SMN | L_PaCL_S (L_SomMotA_19) | CEN | L_MFG (L_DefaultB_PFCl_2) | 147 | 3.96 | 1.16E−04 | 0.03 | Greater |
| SMN | R_PosCG (R_DorsAttnB_PostC_1) | CEN | L_IntPS_TrPS (L_ContB_IPL_3) | 147 | − 3.66 | 3.51E−04 | 0.04 | Lower |
| SMN | L_PRCG, (L_SomMotA_13) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | 3.67 | 3.39E−04 | 0.03 | Greater |
| SMN | R_CS, (R_SomMotA_10) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | 3.23 | 1.53E−03 | 0.04 | Greater |
| SMN | L_PaCL_S, (L_SomMotA_19) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | 3.50 | 6.16E−04 | 0.03 | Greater |
| SMN | R_PRCG, (R_SomMotA_14) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | 3.44 | 7.57E−04 | 0.03 | Greater |
| SMN | R_PosCG, (R_SomMotA_6) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | 3.33 | 1.10E−03 | 0.04 | Greater |
| SMN | R_SupFG, (R_ContB_PFCmp_1) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | − 3.98 | 1.08E−04 | 0.04 | Lower |
| SMN | L_SupFG, (L_ContB_PFCmp_1) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | − 3.56 | 5.00E−04 | 0.03 | Lower |
| Central executive network (CEN) connections | ||||||||
| CEN | R_MFG, (R_ContB_PFCld_4) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | − 3.63 | 3.91E−04 | 0.03 | Lower |
| CEN | L_SbPS, (L_DefaultA_pCunPCC_7) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | − 3.38 | 9.28E−04 | 0.04 | Lower |
| CEN | L_IntPS_TrPS, (L_ContB_IPL_3) | DMN | R_SuMarG, (R_SalVentAttnA_ParOper_2) | 147 | − 3.96 | 1.16E−04 | 0.04 | Lower |
| CEN | L_IntPS_TrPS, (L_ContB_IPL_3) | DMN | R_SuMarG, (R_SalVentAttnA_ParOper_1) | 147 | − 3.68 | 3.27E−04 | 0.04 | Lower |
| CEN | L_IntPS_TrPS, (L_ContB_IPL_3) | DMN | R_SuMarG, (R_SalVentAttnA_ParOper_3) | 147 | − 3.60 | 4.34E−04 | 0.04 | Lower |
| CEN | L_IntPS_TrPS, (L_ContB_IPL_3) | DMN | L_SuMarG, (L_SalVentAttnA_ParOper_1) | 147 | − 3.63 | 3.91E−04 | 0.04 | Lower |
| Default mode network (DMN) connections | ||||||||
| DMN | R_SuMarG, (R_TempPar_10) | DMN | R_PrCun, (R_ContC_pCun_3) | 147 | − 4.37 | 2.34E−05 | 0.01 | Lower |
| DMN | R_PrCun, (R_ContC_pCun_3) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | − 3.70 | 3.04E−04 | 0.03 | Lower |
| DMN | L_PrCun, (L_ContC_pCun_3) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | − 3.62 | 4.05E−04 | 0.03 | Lower |
| DMN | R_AngG, (R_ContB_IPL_2) | DMN | L_SupTGLp, (L_TempPar_6) | 147 | − 3.59 | 4.50E−04 | 0.03 | Lower |
| DMN | R_Tpo, (R_LimbicA_TempPole_1) | DMN | R_SuMarG, (R_SalVentAttnA_ParOper_2) | 147 | 3.87 | 1.63E−04 | 0.04 | Greater |
| DMN | L_SupTGLp, (L_TempPar_6) | DMN | L_MPosCgG_S, (L_SomMotA_1) | 147 | 3.31 | 1.17E−03 | 0.04 | Greater |
Summarizes significant sex-related differences in functional connectivity (females with food addiction vs. males with food addiction). All connections are significant q < 0.05.
AngG, Angular gyrus; CEN, Central Executive Network; CS, Central sulcus (Rolando's fissure); DMN, Default Mode Network; ERN, Emotional Regulation Network; InfFGTrip, Triangular part of the inferior frontal gyrus; IntPS_TrPS, Intraparietal sulcus(interparietal sulcus) and transverse parietal sulci; MFG, Middle frontal gyrus; MOcS_LuS, Middle occipital sulcus and lunatus sulcus; MPosCgG_S, Middle-posterior part of the cingulate gyrus and sulcus; PaCL_S, Paracentral lobule and sulcus; PosCG, Postcentral Gyrus; PRCG, Precentral gyrus; PrCun, Precuneus; ShoInG, Short insular gyri; Tpo, temporal pole; SAL, Salience Network SbPS, Subparietal sulcus; SMN, Sensorimotor Network; SupFG, Superior frontal gyrus; SuMarG, Supramarginal gyrus; SupTGLp, Lateral aspect of the superior temporal gyrus.
df: degrees of freedom; p value significant < .05, q value (corrected for multiple comparisons) < .05.