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. 2021 Jan 27;9:575724. doi: 10.3389/fbioe.2021.575724

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Copyright © 2021 Fu, Wang, Tan and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BRS alters the composition based on OTUs and the relative abundance of gut microbiota at the phylum level. (A) Principal component analysis (PCA) of gut microbiota based on OTUs. The abscissa represents the first principal component, the ordinate represents the second principal component, and the percentage represents the contribution of the principal component to the sample difference. Each point in the figure represents a sample, and samples from the same group are represented in the same color. (B) Bacterial taxonomic profiling at the phylum level of gut microbiota. (C) Bacteroidetes, (D) Firmicutes, (E) Bacteroidetes/Firmicutes ratio, (F) Deferribacteres, (G) Tenericutes, and (H) Cyanobacteria. Differences were based on ANOVA analysis followed by LSD post hoc test and denoted in graph bars as follows: ^∗p < 0.05 and ^∗∗p < 0.01 compared with NC; #p < 0.05 and ##p < 0.01 compared with MC.