Table 2.

Baseline characteristics

Dose‐Level	Sex	Age	ECOG status	Prior systemic therapies	Tumor type	Enrolled	Completed DLT period
1	F	51	1	2	Urothelial	Yes	No
1	M	77	1	3	NET a of pancreas	Yes	Yes
1	F	49	1	3	SCC b of unknown primary	Yes	Yes
1	M	70	1	2	Salivary duct	Yes	Yes
2	M	56	NA	7	NETa of unknown primary	No	Screen failure
2	F	56	1	4	Ovarian	Yes	Yes
2	F	59	NA	1	Pancreas	No	Screen failure
2	M	69	1	0	Colorectal	Yes	Yes
2	M	59	NA	0	Gastric	No	Screen failure
2	M	70	1	4	Gastric	Yes	Yes
3A	F	67	1	3	Pleiomorphic adenoma	Yes	Yes
3A	F	68	1	4	Metaplastic carcinoma	Yes	Yes
3A	M	68	2	3	Glioblastoma	Yes	No
3A	M	67	1	3	Tongue base	Yes	Yes
3B	F	59	1	2	Colorectal	Yes	No
3B	M	60	1	6	Colorectal	Yes	Yes
3B	F	78	1	2	Colorectal	Yes	Yes
3B	M	55	1	3	Tonsil	Yes	Yes
4	M	54	1	1	Colorectal	Yes	No
4	M	64	2	3	Oropharynx and esophageal	Yes	No
4	F	62	1	1	Ovarian	Yes	No
4	M	66	1	6	Hepatocellular	Yes	No
4	M	70	1	1	Colorectal	Yes	Yes
4	M	63	1	1	Hypopharynx	Yes	Yes
4	F	40	1	3	Breast	Yes	No
4	M	77	1	5	Esophageal	Yes	Yes
5	M	69	1	9	Hepatocellular	Yes	Yes
5	M	60	0	2	Colorectal	Yes	Yes
5	M	71	1	3	Prostate	Yes	No
5	F	72	1	3	Breast	Yes	Yes

Abbreviations: ECOG, Eastern Cooperative Oncology Group; F, female; M, male; NA, not applicable; NET.

^aneuroendocrine tumor.

^bsquamous cell carcinoma.