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. 2020 Jul 13;107(4):320–325. doi: 10.1136/heartjnl-2020-317009

Table 2.

Circadian variations of hourly data of AAD onsets, fitted by Fourier model

Group N Nocturnal trough n Morning peak n Afternoon peak n R squared P value
Total 1517 2:52 37.824±11.747 9:27 68.506±11.747 16:41 96.015±11.747 0.8151 0.0008
Type A 737 2:36 15.432±7.618 8:29 37.323±7.618 16:41 44.097±7.618 0.7203 0.0052
Type B 780 4:03 21.304±8.914 10:00 31.192±8.914 16:41 51.917±8.914 0.7204 0.0143
Male 1242 2:50 29.235±9.248 9:53 56.591±9.248 16:39 79.225±9.248 0.826 0.0004
Female 275 4:58 7.063±5.282 8:46 12.500±5.282 18:29 17.290±5.282 0.5518 0.1641
Age <55 years 875 4:07 23.327±10.628 8:54 40.316±10.628 16:51 52.087±10.628 0.5849 0.0803
Age ≥55 years 642 2:18 11.387±4.919 10:40 29.974±4.919 16:34 44.026±4.919 0.8766 <0.0001
Hypertensive 929 3:02 23.861±9.927 7:00 36.635±9.927 16:50 61.886±9.927 0.7238 0.0088
Normotensive 577 1:57 13.552±4.843 9:32 34.235±4.843 16:14 33.659±4.843 0.8375 0.0002

Letter N indicates the number of cases in each group; letter n shows the number of cases fitted by Fourier model, presented by numbers±95% CIs; R square represents goodness of the model; and P, probability value resulting from the F statistic used to test hypothesis of straight-line model fitting.

AAD, acute aortic dissection.