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. 2020 Aug 27;70(3):606–617. doi: 10.1136/gutjnl-2019-319984

Table 1.

Frequency of the most common deleteriously mutated genes in familial pancreatic cancer

Gene Zhen et al 44 (n=515) Roberts et al 22 (n=166) Takai et al 45 (n=54) Mutation prevalence (%)
BRCA2 19 n.a. 3 3.9
ATM n.a. 4 2 2.7
CDKN2A 13 n.a. n.a. 2.5
BRCA1 6 n.a. n.a. 1.2
PALB2 3 n.a. 2 0.9

Mutations data were analysed from three familial pancreatic cancer cohorts (735 samples).

n.a., not applicable.