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. 2020 Sep 16;107(4):313–318. doi: 10.1136/heartjnl-2020-317165

Table 1.

Baseline characteristics of patients with and without recurrent AMI after initial AMI

All patients Recurrent AMI No recurrent AMI P value
N=3387 n=84 n=3303
Sociodemographics
 Age, mean (SD) 60.7 (11.9) 66.2 (12.8) 60.5 (11.8) <0.001
 Age category, years, n (%) <0.001
 18–44 307 (9.1) 5 (6.0) 302 (9.1)
 45–64 1774 (52.4) 26 (31.0) 1748 (52.9)
 65–74 861 (25.4) 29 (34.5) 832 (25.2)
 75–84 407 (12.0) 24 (28.6) 383 (11.6)
 ≥85 38 (1.1) 0 (0.0) 38 (1.2)
 Female, n (%) 783 (23.1) 28 (33.3) 755 (22.9) 0.025
 College degree, n (%) 462 (13.6) 9 (10.7) 453 (13.7) 0.429
 Employed, n (%) 1420 (41.9) 20 (23.8) 1400 (42.4) <0.001
Medical history and comorbidities, n (%)
 History of angina 134 (4.0) 7 (8.3) 127 (3.8) 0.037
 History of acute myocardial infarction 267 (7.9) 12 (14.3) 255 (7.7) 0.027
 History of heart failure 787 (23.2) 33 (39.3) 754 (22.8) <0.001
 Dyslipidaemia 1885 (55.7) 58 (69.0) 1827 (55.3) 0.012
 Hypertension 230 (6.8) 12 (14.3) 218 (6.6) 0.006
 Diabetes 1005 (29.7) 36 (42.9) 969 (29.3) 0.007
 Renal dysfunction 694 (20.5) 33 (39.3) 661 (20.0) <0.001
Clinical characteristics, n (%)
 Systolic blood pressure at admission <100 mm Hg 264 (7.8) 6 (7.1) 258 (7.8) 0.822
 Heart rate at admission >90 beats/min 450 (13.3) 21 (25.0) 429 (13.0) 0.001
 Ejection fraction <40% 245 (7.2) 8 (9.5) 237 (7.2) 0.412
 ST-segment elevation AMI 2768 (81.7) 61 (72.6) 2707 (82.0) 0.029
Reperfusion therapies, n (%)
 PCI 2363 (69.8) 33 (39.3) 2330 (70.5) <0.001
 Thrombolytic therapy 489 (14.4) 11 (13.1) 478 (14.5) 0.723
In-hospital medications, n (%)
 Aspirin 3085 (91.1) 79 (94.0) 3006 (91.0) 0.334
 Clopidogrel 3231 (95.4) 74 (88.1) 3157 (95.6) 0.001
 Beta-blocker 2759 (81.5) 67 (79.8) 2692 (81.5) 0.685
 ACEI/ARB 2486 (73.4) 54 (64.3) 2432 (73.6) 0.056
 Statin 3337 (98.5) 80 (95.2) 3257 (98.6) 0.012
Discharge medications, n (%)
 Aspirin 3187 (94.1) 73 (86.9) 3114 (94.3) 0.005
 Clopidogrel 3088 (91.2) 70 (83.3) 3018 (91.4) 0.01
 Beta-blocker 2376 (70.2) 60 (71.4) 2316 (70.1) 0.796
 ACEI/ARB 2136 (63.1) 52 (61.9) 2084 (63.1) 0.824
 Statin 3193 (94.3) 74 (88.1) 3119 (94.4) 0.014
 Length of stay, median (IQR) 11 (8 to 14) 12 (8 to 14.5) 11 (8 to 14) 0.286

ACEI, angiotensin-converting enzyme inhibitor; AMI, acute myocardial infarction; ARB, angiotensin receptor blocker; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention.