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. 2020 Jun 14;70(3):499–510. doi: 10.1136/gutjnl-2020-321106

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Factors explaining microbiota variance. Association between 25 tested environmental factors and the microbiota beta diversity of n=650 individuals (291 Crohn’s disease (CD), 236 ulcerative colitis (UC), 120 controls; one randomly chosen time point per subject) at operational taxonomic unit (OTU) level in terms of explained fraction of the variance in Bray-Curtis dissimilarity. Of available 692 subjects, 42 were excluded due to missing values in the metadata. Adjusted permutational multivariate analysis of variance p values: *p<0.05; **p<0.01; ***p<0.001. 5-ASA, 5-aminosalicylic acid; NSAID, non-steroidal anti-inflammatory drug; NS, not significant.