Table 2.
Markers for T-cells imaging.
| Category | Name | Reference and clinical trials |
|---|---|---|
| T cell surface | Interleukin-2 receptor alpha chain (CD25) | NCT02922283 (357, 358, 365–367) |
| OX40 receptor (CD134) | NCT02318394 (359, 368) | |
| T cell receptor (TCR) | (361, 369, 370) | |
| CD3 | (351, 371, 372) | |
| CD4 | (362) | |
| CD8 |
NCT03107663, NCT03802123, NCT03610061 (347, 363, 364) |
|
| Metabolic pathways | L-leucine analogue | (373–375) |
| 18F-FAC | (376–378) | |
| 18F -CFA | NCT03409419 (377, 379–381) | |
| 18F-FLT | (382–384) | |
| 18F-F-AraG |
NCT03311672, NCT03142204, NCT03007719 (385, 386) |
|
| 18F-FDG | (387–391) | |
| Effector function | Granzyme B | (392–395) |
| Interferon-gamma | (396) | |
| Checkpoint receptors |
NCT03065764, NCT02760225, NCT03313323 (397–399) |