Table 4.

Cytotoxicity of compounds against tumor cell lines (IC₅₀ ± SEM, nM)^a.

Compound	RPMI8226	THP-1	Ramos (RA 1)	SW480	Hela	MGC-803
25	455.0 ± 42.1	567.9 ± 49.48	464.0 ± 9.53	2441 ± 123.9	8701 ± 1195	2017 ± 123.4
26	474.8 ± 53.3	475.4 ± 53.17	428.1 ± 7.28	2002 ± 213.2	3202 ± 47.62	1164 ± 4.74
35	90.99 ± 11.1	78.12 ± 1.09	38.35 ± 2.46	94.25 ± 4.77	448.9 ± 5.89	88.80 ± 5.01
43	40.41 ± 3.23	71.12 ± 2.02	45.73 ± 3.46	82.86 ± 4.67	211.8 ± 4.29	78.51 ± 7.46
44	37.57 ± 2.46	70.67 ± 6.11	26.92 ± 0.40	72.55 ± 7.54	120.0 ± 8.80	68.54 ± 7.04
46	38.11 ± 1.19	94.41 ± 1.45	26.13 ± 0.18	79.26 ± 1.87	260.4 ± 4.34	79.05 ± 12.59
47	43.4 ± 1.04	97.86 ± 2.79	38.33 ± 3.04	74.50 ± 3.13	238.93 ± 3.28	85.40 ± 6.73
BSc2198	67.76 ± 5.79	88.07 ± 3.85	53.6 ± 2.21	106.3 ± 14.93	288.3 ± 25.22	118.8 ± 3.63

^aThe IC₅₀ was calculated with assay data measured at 7 concentrations while each value was determined from three independent experiments.