Table 3.
Multivariate analysis of factors potentially associated with overall survival Model 1 (TLC included)
| Model 1 (TLC Included) | Model 2 (NLR Included) | Model 3 (PLR Included) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | HR | 95% CI | P Value | |
| Characteristics | |||||||||
| Age ≥65 | 0.902 | 0.697-1.167 | 0.431 | 0.858 | 0.67-1.099 | 0.226 | 0.825 | 0.645-1.054 | 0.124 |
| Pretreatment TLC ≥2.4 × 103/μL | 0.613 | 0.474-0.794 | <0.001 | ||||||
| Pretreatment NLR ≥3.4 | 2.231 | 1.734-2.87 | <0.001 | ||||||
| Pretreatment PLR ≥136.1 | 1.71 | 1.333-2.185 | <0.001 | ||||||
Abbreviations: HR, hazard ratio; CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; TNM, tumor-nodes-metastasis; TLC, total lymphocyte count; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.