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. 2021 Jan 27;10:599204. doi: 10.3389/fonc.2020.599204

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Copyright © 2021 Penet, Kakkad, Wildes and Bhujwalla

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Percent water content and (B) wet weight over dry weight ratio in different tissues identifying higher water content in tumors compared to the pancreas and other organs. Healthy organs n=4, Panc1 tumors n=2 (orthotopic n=1, subcutaneous n=1), BxPC3 tumors n=5 (orthotopic n=3, subcutaneous n=2). Values represent Mean +/− SD. One-way ANOVA: P < 0.0001. Dunnett’s multiple comparison test: ^#p < 0.01, ^##p < 0.001, ^###p < 0.0001 for comparison to Panc1 tumors; *p < 0.01, ^**p < 0.001, ^***p < 0.0001 for comparison to BxPC3 tumors.