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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: DNA Repair (Amst). 2020 Apr 27;94:102860. doi: 10.1016/j.dnarep.2020.102860

Fig. 4.

Fig. 4.

DDB2 interactome prepared in BioGRID. Human DDB2 was selected and the minimum evidence was set to 5. The interactome network centered on DDB2 (red) was created using an arbor layout. Nodes in blue = 28 are DDB1 and/or DDB2 interacting proteins in human cells. Some low interacting nodes were trimmed out of the network. These interactors are shown in yellow for direct physical evidence. Greater node size represents increased connectivity and thicker edge sizes represent increased evidence supporting the association. VPR node is in yellow and is a major HIV protein that interacts with DDB1 to help direct the ubiquitination and degradation of key cellular proteins to aid in HIV infection.