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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: DNA Repair (Amst). 2020 Apr 27;94:102860. doi: 10.1016/j.dnarep.2020.102860

Fig. 6.

Fig. 6.

Association of decreased DDB2 mRNA expression with increased cancer risk. (A) The Human Protein Atlas was queried for DDB2 under the Pathology tab. The prognostic summary reached high significance for patient survival in three cancer types: endometrial, cervical, and breast. Low mRNA expression (blue) indicated a poor prognosis as compared to high (pink) mRNA expression levels of DDB2. Other cancers sites showing a similar trend using Kplot.com [98], included, kidney renal clear and papillary cell, liver, lung, sarcoma, stomach, and thyroid. Linn and colleagues showed that DDB2 heterozygous and knockout mice have decreased overall survival (B) and tumor-free survival (C). From [77] with permission.