Table 4. Adverse Events Among the As-Randomized Population in a Study of the Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Patients With Acute Myocardial Infarction and Anemia.
Adverse event | No. (%) | |
---|---|---|
Restrictive (n = 342) | Liberal (n = 324) | |
At least 1 adverse event | 40 (11.7) | 36 (11.1) |
Acute kidney injurya | 33 (9.7) | 23 (7.1) |
Acute heart failureb | 11 (3.2) | 12 (3.7) |
Severe allergic reactiona | 3 (0.9) | 0 |
Acute lung injury/ARDSa | 1 (0.3) | 7 (2.2) |
Multiorgan system dysfunctiona | 1 (0.3) | 3 (0.9) |
Infectiona,c | 0 | 5 (1.5) |
Abbreviation: ARDS, acute respiratory distress syndrome.
According to investigator judgment.
Adjudicated according to the following criteria: new or worsening symptoms due to congestive heart failure, objective evidence of new congestive heart failure (physical examination, laboratory, imaging or hemodynamic evidence), and initiation or intensification of chronic heart failure treatment.
Documented bacterial infection/bacteremia acquired at any time after the first transfusion.