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. 2021 Jan 12;11:625659. doi: 10.3389/fgene.2020.625659

Table 3.

Clinical characteristics of patients who received osimertinib at the 3rd Xiangya Hospital.

Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6 Patient 7 Patient 8
Age at osimertinib treatment (years) 73 49 57 71 48 56 81 55
Sex Male Female Male Female Male Male Female Female
Diagnosis Adenocarcinoma of right lung Bronchial adenocarcinoma Adenocarcinoma of right lung Adenocarcinoma of left lung Adenocarcinoma of right lung Lung cancer* Lung cancer* Lung cancer*
Duration of cancer history 1 month 4 months 12 months 12 months 20 months 1 months 10 months 8 months
Complications Benign prostatic hyperplasia / COPD Hypertension CKD; hypertension / Postoperative colon cancer; gallstone; remote cerebral infarction /
Drug combination Tiotropium bromide, tamsulosin, finasteride / Morphine, ampeptide elemente Tramadol, celecoxib Ulbenemax, mosapride, calcium malate, montelukast / Mecobalamin, trimetazidine, magnesium potassium aspartate, atorvastatin, aspirin /
Relative gene Undetected EGFR (–) EGFR (+) EGFR (+) EGFR (+) Undetected EGFR (+) EGFR (–)
Metastasis site Adrenal gland; bone; mediastinal lymph nodes; pleura; right subclavian lymph nodes Lung; pleura Mediastinal lymph nodes; right subclavian lymph nodes Bone; liver Lymph nodes; pericardium; pleura; enterocoelia Bone; lung No metastasis Adrenal gland; bone; brain
Relative gene Undetected EGFR (–) EGFR (+) EGFR (+) EGFR (+) Undetected EGFR (+) EGFR (–)
Start date of osimertinib treatment 2016/12/28 2019/1/29 2019/12/10 2019/6/20 2019/10/28 2020/4/15 2020/4/22 2019/10/13
Follow-up time 5 months 6 months 2 months 14 months 7 months 1 months 5 months 7 months
*

= Without pathological diagnosis; / = Not mentioned in the electronic health records.