Table 3.
Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Patient 8 | |
---|---|---|---|---|---|---|---|---|
Age at osimertinib treatment (years) | 73 | 49 | 57 | 71 | 48 | 56 | 81 | 55 |
Sex | Male | Female | Male | Female | Male | Male | Female | Female |
Diagnosis | Adenocarcinoma of right lung | Bronchial adenocarcinoma | Adenocarcinoma of right lung | Adenocarcinoma of left lung | Adenocarcinoma of right lung | Lung cancer* | Lung cancer* | Lung cancer* |
Duration of cancer history | 1 month | 4 months | 12 months | 12 months | 20 months | 1 months | 10 months | 8 months |
Complications | Benign prostatic hyperplasia | / | COPD | Hypertension | CKD; hypertension | / | Postoperative colon cancer; gallstone; remote cerebral infarction | / |
Drug combination | Tiotropium bromide, tamsulosin, finasteride | / | Morphine, ampeptide elemente | Tramadol, celecoxib | Ulbenemax, mosapride, calcium malate, montelukast | / | Mecobalamin, trimetazidine, magnesium potassium aspartate, atorvastatin, aspirin | / |
Relative gene | Undetected | EGFR (–) | EGFR (+) | EGFR (+) | EGFR (+) | Undetected | EGFR (+) | EGFR (–) |
Metastasis site | Adrenal gland; bone; mediastinal lymph nodes; pleura; right subclavian lymph nodes | Lung; pleura | Mediastinal lymph nodes; right subclavian lymph nodes | Bone; liver | Lymph nodes; pericardium; pleura; enterocoelia | Bone; lung | No metastasis | Adrenal gland; bone; brain |
Relative gene | Undetected | EGFR (–) | EGFR (+) | EGFR (+) | EGFR (+) | Undetected | EGFR (+) | EGFR (–) |
Start date of osimertinib treatment | 2016/12/28 | 2019/1/29 | 2019/12/10 | 2019/6/20 | 2019/10/28 | 2020/4/15 | 2020/4/22 | 2019/10/13 |
Follow-up time | 5 months | 6 months | 2 months | 14 months | 7 months | 1 months | 5 months | 7 months |
= Without pathological diagnosis; / = Not mentioned in the electronic health records.