Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 21;11:599869. doi: 10.3389/fendo.2020.599869

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Gannon, O’Hara, Mason, Jørgensen, Frederiksen, Curley, Milne, Smith, Mitchell and Smith

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Fewer proliferating cells are observed on G1 and G2 Ad-ARKO females compared to WT controls. (A, D) Investigation of apoptosis revealed no changes in either G1 or G2 Ad-ARKO females when compared to WT controls. Confirmation through cell counts reveals no changes in cell death in G1or G2 Ad-ARKO females compared to WT controls. (B, C) Immunostaining of PCNA localization and cell counts reveal fewer proliferating cells in G1and G2 Ad-ARKO females compared to WT controls. (E) Immunostaining of 3βHSD localization reveals that sections of the ZG do not express 3βHSD in G1 or G2 Ad-ARKO females, compared to WT controls that are positive in both the ZG and ZF. (*) denotes insert location. N=5. All mice collected and analyzed at d80. Scale Bars 100 µm. Annotations; M, medulla; ZF, zona fasciculata; ZG, zona glomerulosa.