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. 2021 Jan 11;13:611179. doi: 10.3389/fnmol.2020.611179

Figure 3.

Figure 3

NMD enhanced acid-sensing ion channel 1 (ASIC1) expression. (A) Expression of ASIC1 in the spinal dorsal horn of T13-L2 in NMD rats compared with CON rats (*P < 0.05, n = 5 rats for CON and n = 4 rats for NMD, two-sample t-test). (B) Expression of ASIC2 in the spinal dorsal horn of T13-L2 in NMD rats compared with CON rats (P > 0.05, n = 5 rats for CON and n = 4 rats for NMD, two-sample t-test). (C) Expression of ASIC1 in the spinal dorsal horn of T7–T10 in NMD rats compared with CON rats (P > 0.05, n = 4 rats for each group, two-sample t-test). (D) Expression of ASIC1 in the spinal dorsal horn of L4–L6 in NMD rats compared with CON rats (P > 0.05, n = 4 rats for each group, two-sample t-test). (E) Location of ASIC1 in the spinal dorsal horn of T13-L2 in NMD rats. (F) Co-localization of ASIC1 and NeuN in the spinal dorsal horn of T13-L2 in CON and NMD rats. (G) Expression of ASIC1 in the spinal dorsal horn of T13-L2 in CON and NMD rats (***P < 0.001, n = 3 rats for each group, two-sample t-test).