Table 3.
MBI-C total and domain scores.
| MBI-C scores Mean, SD (Min–Max) | Val carriers (GG) N = 90 | Met carriers (GA, AA) N = 46 | r2, Beta (CI 95%) | p-value* |
|---|---|---|---|---|
| MBI-C total | 4.06, ±4.50 (0–20) | 7.39, ±8.05 (0–29) | 0.13, 0.25 (1.17–5.35) | 0.003** |
| Drive/motivation | 1.10, ±1.72 (0–8) | 1.43, ±2.02 (0–8) | 0.06, 0.07 (−0.38 to 0.92) | 0.41 |
| Mood/anxiety | 1.48, ±2.21 (0–13) | 2.87, ±3.36 (0–12) | 0.10, 0.24 (0.46–2.35) | 0.004** |
| Impulse dyscontrol | 0.79, ±1.43 (0–8) | 1.15, ±2.80 (0–13) | 0.03, 0.10 (−0.28 to 1.16) | 0.23 |
| Social inappropriateness | 0.16, ±0.62 (0–4) | 0.43, ±1.41 (0–7) | 0.04, 0.14 (−0.07 to 0.63) | 0.11 |
| Abnormal thoughts/perception | 0.53, ±1.09 (0–4) | 1.50, ±2.54 (0–11) | 0.12, 0.23 (0.26–1.48) | 0.006** |
MoCA and UPDRS scores were used in a multiple linear regression model. In total, 10 PD participants were identified as outliers and removed from the analysis.
Val, valine; Met, methionine; MBI-C, mild behavioral impairment checklist; SD, standard deviation; Min, minimum; Max, maximum; MoCA, montreal cognitive assessment; CI 95%, 95% confidence interval.
Analysis was performed using multiple linear regression model including MoCA and UPDRS scores in the model. MoCA and MBI-C total scores were negatively correlated (rp = 0.17, p = 0.043), while UPDRS and MBI-C total scores were positively correlated (rp = 0.23, p = 0.007).
p-value was set to <0.01 to correct for multiple tests, Bonferroni correction.