Table 4.
Multiple logistic regression analysis of BDNF p.Val66Met and MBI positive likelihood after removing participants with total MBI-C score of 7 and 8.
| Covariate | Estimate | SE | Wald's chi square | p-value* | OR | 95% CI |
|---|---|---|---|---|---|---|
| BDNF Met allele | 1.48 | 0.48 | 9.54 | 0.002a* | 4.37 | 1.71–11.14 |
| MoCA | −0.14 | 0.06 | 4.84 | 0.03a | 0.87 | 0.77–0.98 |
| UPDRS-III | 0.04 | 0.02 | 3.76 | 0.053a | 1.04 | 1.00–1.09 |
| Constant | −0.71 | 1.71 | 0.19 | 0.67a | NA | NA |
Ten participants were removed, including only one Met carrier with the score of 7 (n = 126).
Val, valine; Met, methionine; MBI-C, mild behavioral impairment checklist; SE, standard error; OR, odds ratio; CI, confidence interval; NA, not applicable.
a
Multiple logistic regression model, N = 126, Nagelkerke pseudo R2 = 0.24, Hosmer and Lemeshow goodness-of-fit test p = 0.31 (df = 8), correct cases overall percentage = 77.8%.
*
p-value was set to <0.01 corrected for multiple tests, Bonferroni correction.