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. 2021 Jan 13;14:589650. doi: 10.3389/fnins.2020.589650

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Copyright © 2021 He, Qian, Zhang, Huang, Deng, Zhang, Gao, Li, Xie and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of 8-day (A), pair-feeding (8-day) (B), and 36-day (C) olanzapine treatment on the IL-6, IL-1β, and TNF-α levels in plasma. (D) The effect of 4-PBA and olanzapine co-treatment for 8 days on plasma concentrations of IL-6, IL-1β, and TNF-α. Effects of 8-day (E,F), pair-feeding (8-day) (G,H), and 36-day (I,J) olanzapine treatment and 8-day 4-PBA co-treatment (K,L) on the protein expression of IL-6, IL-1β, and TNF-α in the rat periovarian white adipose tissue. All data were presented as mean ± SEM. Statistical significance was defined as p < 0.05 (^$p < 0.05, ^$$p < 0.01, ^$$$p < 0.001 vs. control; ^∗p < 0.05, ^∗∗∗p < 0.001 vs. OLZ). Con, control; OLZ, olanzapine.