Figure 1.

(A) Average annual prevalence of Pseudomonas aeruginosa and Staphylococcus aureus between 2004 and 2017, stratified by age cohorts (in years) defined in the Cystic Fibrosis Foundation Annual Report. Data are from subjects who had at least 10 quantitative cultures (N = 134). Consistent with registry-wide data from the same time interval, P. aeruginosa prevalence is greater than S. aureus prevalence among adult patients. (B) Quantitative culture results for a representative single subject. H. influenzae was present early. MSSA and P. aeruginosa were subsequently identified and remained stable for nearly 10 years. H. influenzae = Haemophilus influenzae; MSSA = methicillin-sensitive Staphylococcus aureus.