Table 2.
Comparison of Raw Scores for Fatigue (PROMIS-F), Sleep Disturbance (PROMIS-SD), and Depression (HDRS) Before and at the end of CRT Between Participants who had Developed Co-Occurring Symptoms by the end of CRT and those who Developed no Symptoms.
| Symptom Measure | 0 Symptoms (n = 7) Median (IQR) |
> 2 Symptoms (n = 24) Median (IQR) |
p-value* |
|---|---|---|---|
| PROMIS-F (possible range: 7–35) | |||
| Before CRT | 16 (13,26) | 15 (11, 22) | 0.50 |
| End of CRT | 14 (10,18) | 24 (20, 28) | 0.001 |
| PROMIS-SD (possible range: 8–40) | |||
| Before CRT | 23 (19, 34) | 22 (13, 28) | 0.27 |
| End of CRT | 21 (8, 29) | 28 (20, 34) | 0.09 |
| HDRS (possible range: 0–50) | |||
| Before CRT | 7 (5, 9) | 7 (9, 8) | 0.90 |
| End of CRT | 7 (5, 12) | 10 (4, 19) | 0.46 |
Note. CRT = chemotherapy and radiation therapy; HDRS = Hamilton Depression Rating Scale; PROMIS-F = Patient-Reported Outcome Measures Information System-fatigue; PROMIS-SD = Patient-Reported Outcome Measures Information System-sleep disturbance.
*Represents the p-value of a double-tailed Mann-Whitney test.