Table 2.
Estimated Mean (SE) Changes from Baseline in Body Weight, AHI, and Waist Circumference at 1, 2, 4, and 10 Years
Measure | Year | Intensive Lifestyle Intervention Group | P Value* | Diabetes Support and Education Group | P Value* | Between Groups | P Value† |
---|---|---|---|---|---|---|---|
AHI, events/h | 1 | −5.5 ± 1.4 | 0.0001 | 4.3 ± 1.4 | 0.0017 | −9.7 ± 2.0 | <0.0001 |
2 | −3.6 ± 1.5 | 0.0133 | 4.4 ± 1.4 | 0.0014 | −8.0 ± 2.0 | <0.0001 | |
4 | −3.8 ± 1.6 | 0.0149 | 4.0 ± 1.5 | 0.0093 | −7.9 ± 2.2 | 0.0004 | |
10 | −9.9 ± 1.8 | <0.0001 | −5.9 ± 1.8 | 0.0011 | −4.0 ± 2.5 | 0.1088 | |
Weight, kg | 1 | −10.7 ± 0.7 | <0.0001 | −0.5 ± 0.7 | 0.514 | −10.2 ± 1.0 | <0.0001 |
2 | −7.4 ± 0.7 | <0.0001 | −0.8 ± 0.7 | 0.255 | −6.6 ± 1.0 | <0.0001 | |
4 | −5.1 ± 0.7 | <0.0001 | −0.9 ± 0.7 | 0.225 | −4.3 ± 1.0 | <0.0001 | |
10 | −7.1 ± 0.8 | <0.0001 | −3.5 ± 0.8 | <0.0001 | −3.6 ± 1.1 | 0.001 | |
Waist circumference, cm | 1 | −9.0 ± 0.7 | <0.0001 | −0.6 ± 0.7 | 0.376 | −8.4 ± 1.0 | <0.0001 |
2 | −5.9 ± 0.7 | <0.0001 | −0.7 ± 0.7 | 0.306 | −5.2 ± 1.0 | <0.0001 | |
4 | −3.4 ± 0.7 | <0.0001 | 0.2 ± 0.7 | 0.731 | −3.6 ± 1.0 | 0.000 | |
10 | −2.1 ± 0.8 | 0.010 | 1.6 ± 0.8 | 0.047 | −3.7 ± 1.1 | 0.001 |
Definition of abbreviation: AHI = apnea–hypopnea index.
Compared with baseline value.
Between-group comparison.