Figure 2.
Silencing of PVT1 inhibited CC progression. CC HeLa and SIHA cells were transfected with control (blank), si-NC, or si-PVT1. (a) PVT1 expression in transfected HeLa and SIHA cells evaluated via qRT-PCR assay at 48 h post transfection. (b and c) Cell viability in HeLa and SIHA cells analyzed by MTT assay at 24, 48, and 72 h post transfection. (d) Cell apoptosis rate of transfected HeLa and SIHA cells evaluated by flow cytometry. (e and f) Cell migration and invasion examined by Transwell assay. *P < 0.05. All experiments were repeated thrice, independently.